Tuesday, February 18, 2020

Methods available for the assessment of alcohol abuse Essay

Methods available for the assessment of alcohol abuse - Essay Example neurotransmitters like the opioid systems, dopamine, serotonin and gamma-amino-butyric acid (GABA) and their interactions are most affected (Chastain 2006). Being volatile, alcohol can be inhaled during ingestion and freely diffused into the airways (George, et al. 1996). This property became the basis for the breath test for estimating levels of blood alcohol (Hlastala 1998). Changes in levels of important enzymes were based on the effect of alcohol on hepatic functions and characteristics (Purohit and Brenner 2006) and other diseases (Purohit, Khalsa and Serrano, 2005). Liver damage due to alcohol has been attributed to increased oxidative stress which could be due to alterations in the liver’s antioxidant defense mechanism. Chronic ethanol intake was found to decrease cytosolic and mitochondrial glutathione/glutathione peroxidase-1 activities by 40% and 30%, respectively thereby promoting the oxidative modification of liver proteins (Bailey, et al. 2006) (Cunningham and Bai ley 2001). The long-term mean daily intake of 61.6 g of ethanol increases the frequency for fatty liver and alcoholic hepatitis (Savolainen, et al. 2007). Ethanol transfers from the blood into the air sacs in the lungs, and thus, consumption can be routinely determined by what is known as the breath test (Hlastala 1998). The breath alcohol concentration predicts the blood alcohol concentration at certain time points. The development of breath testing instruments (â€Å"breathalyzers†) has resulted in a low-cost, accurate, rapid and painless ethanol quantification. The level of alcohol exhaled is then multiplied with a factor to get an approximation of blood alcohol. However, many factors can affect the breathalyzer results; among these is diabetes (which can increase blood alcohol levels due to ketogenic reactions in the body (Berg, Tymoczko and Stryer 2002). In emergency cases where a breath test is not suitable, ethanol concentrations can be determined from blood, urine and saliva

Monday, February 3, 2020

Oral Language and Code-Related Precursors to Reading Essay

Oral Language and Code-Related Precursors to Reading - Essay Example Juan describes his interests as playing basketball, swimming, and fishing, which he normally undertake with his family, particularly his father and brother. He claims to have a big difficulty in school though, specifically in reading and writing English words. He says that way back in Mexico, he used to appreciate Science, but right now where every subject matter including Science needs to be learned and understood in the English language, he begins to dislike the subject matter. He has average scores in Math concepts exhibited by his scores in quizzes and long examinations. He is however poor in word attack and English vocabulary, which affects his performance in other subjects including Science, which used to be his favorite. Â  I was able to talk to Juan’s aunt once, upon visiting Juan and gathering information from his family about things related to his reading progress. This is where I found that both of Juan’s parents live in Mexico and had little schooling. The aunt related that both boys frequently scan their notes upon arriving home and practice reading orally. However, there are some questions that she could not answer, such as the correct pronunciation of a word or the meaning of a particular word, or if the sentence the boys have just uttered is grammatically correct, since she herself has a limitation in the English language as she just migrated to the United States five months ago. Juan is thus left with only the school to rely on when learning to read. Â  Juan appears to be persevering during reading sessions and tries hard to understand each word. Often, when he could not pronounce a word, he approaches me and asks how it is pronounced. He repeatedly utters the new-learned word until he thinks it sinks in.